Disable multicast polling and the MSMQ problem should go away. You may also have to clean out (orphaned .mq files) the MSMQ (C:\Windows\system32\msmq\storage). Multicast is not ready for prime time!!! A buddy-drop is being developed for us for 10.6.1 to try. Supposedly, it is fixed in 10.7 but that's to be seen.
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